Cupramine 100ml. Effectively eradicates ectoparasites of both freshwater and marine fish. It has all the advantages of copper sulfate and chelated copper, but none of the disadvantages. Shared advantages: 1. It is fully ionic and effective at low concentrations. 2. Safe for fish, and is not precipitated in the filter bed. Unique advantages: 1. There is more than a 4-fold concentration gap between the minimal therapeutic dose (0.2 mg - L) and the toxic does (0.8 mg - L), it is stable in the aquarium, it is easily removed by chemical filtration, it is highly effective and safe in freshwater as well as marine water, and, it does not damage the filter bed. 100 mL treats 2,000 L (500 gallons). Test for copper with MultiTest: Copper Kit. Marine or freshwater use